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<?php
/**
 * File: Root_Loader.php
 *
 * @package W3TC
 */

namespace W3TC;

/**
 * Class: Root_Loader
 *
 * phpcs:disable PSR2.Classes.PropertyDeclaration.Underscore
 */
class Root_Loader {
	/**
	 * Enabled Plugins that has been run
	 *
	 * @var W3_Plugin[]
	 */
	private $_loaded_plugins = array();

	/**
	 * Enabled extensions that has been run
	 *
	 * @var W3_Plugin[]
	 */
	private $_loaded_extensions = array();

	/**
	 * Constructor.
	 */
	public function __construct() {
		$c = Dispatcher::config();

		$plugins   = array();
		$plugins[] = new Generic_Plugin();

		if ( $c->get_boolean( 'dbcache.enabled' ) ) {
			$plugins[] = new DbCache_Plugin();
		}

		if ( $c->getf_boolean( 'objectcache.enabled' ) ) {
			$plugins[] = new ObjectCache_Plugin();
		}

		if ( $c->get_boolean( 'pgcache.enabled' ) ) {
			$plugins[] = new PgCache_Plugin();
		}

		if ( $c->get_boolean( 'cdn.enabled' ) ) {
			$plugins[] = new Cdn_Plugin();
		}

		if ( $c->get_boolean( 'cdnfsd.enabled' ) ) {
			$plugins[] = new Cdnfsd_Plugin();
		}

		if ( $c->get_boolean( 'lazyload.enabled' ) ) {
			$plugins[] = new UserExperience_LazyLoad_Plugin();
		}

		if ( $c->get_boolean( 'browsercache.enabled' ) ) {
			$plugins[] = new BrowserCache_Plugin();
		}

		if ( $c->get_boolean( 'minify.enabled' ) ) {
			$plugins[] = new Minify_Plugin();
		}

		if ( $c->get_boolean( 'varnish.enabled' ) ) {
			$plugins[] = new Varnish_Plugin();
		}

		if ( $c->get_boolean( 'stats.enabled' ) ) {
			$plugins[] = new UsageStatistics_Plugin();
		}

		if ( is_admin() ) {
			$plugins[] = new Generic_Plugin_Admin();
			$plugins[] = new BrowserCache_Plugin_Admin();
			$plugins[] = new DbCache_Plugin_Admin();
			$plugins[] = new UserExperience_Plugin_Admin();
			$plugins[] = new ObjectCache_Plugin_Admin();
			$plugins[] = new PgCache_Plugin_Admin();
			$plugins[] = new Minify_Plugin_Admin();
			$plugins[] = new Generic_WidgetSpreadTheWord_Plugin();
			$plugins[] = new SystemOpCache_Plugin_Admin();

			$plugins[] = new Cdn_Plugin_Admin();
			$plugins[] = new Cdnfsd_Plugin_Admin();

			$cdn_engine = $c->get_string( 'cdn.engine' );

			$plugins[] = new PageSpeed_Api();
			$plugins[] = new PageSpeed_Page();
			$plugins[] = new PageSpeed_Widget();

			$plugins[] = new Generic_Plugin_AdminCompatibility();
			$plugins[] = new Licensing_Plugin_Admin();

			if ( $c->get_boolean( 'pgcache.enabled' ) || $c->get_boolean( 'varnish.enabled' ) ) {
				$plugins[] = new Generic_Plugin_AdminRowActions();
			}

			$plugins[] = new Extensions_Plugin_Admin();
			$plugins[] = new UsageStatistics_Plugin_Admin();
			$plugins[] = new SetupGuide_Plugin_Admin();
			$plugins[] = new FeatureShowcase_Plugin_Admin();
		} else {
			if ( $c->get_boolean( 'jquerymigrate.disabled' ) ) {
				$plugins[] = new UserExperience_Plugin_Jquery();
			}
		}

		$this->_loaded_plugins = $plugins;

		register_activation_hook(
			W3TC_FILE,
			array( $this, 'activate' )
		);

		register_deactivation_hook(
			W3TC_FILE,
			array( $this, 'deactivate' )
		);
	}

	/**
	 * Run plugins
	 */
	public function run() {
		foreach ( $this->_loaded_plugins as $plugin ) {
			$plugin->run();
		}

		if ( method_exists( $GLOBALS['wpdb'], 'on_w3tc_plugins_loaded' ) ) {
			$o = $GLOBALS['wpdb'];
			$o->on_w3tc_plugins_loaded();
		}

		$this->run_extensions();
	}

	/**
	 * Activation action hook
	 *
	 * @param bool $network_wide Network wide flag.
	 */
	public function activate( $network_wide ) {
		Root_AdminActivation::activate( $network_wide );
	}

	/**
	 * Deactivation action hook
	 */
	public function deactivate() {
		Root_AdminActivation::deactivate();
	}

	/**
	 * Loads extensions stored in config
	 */
	public function run_extensions() {
		$c          = Dispatcher::config();
		$extensions = $c->get_array( 'extensions.active' );

		$frontend = $c->get_array( 'extensions.active_frontend' );
		foreach ( $frontend as $extension => $nothing ) {
			if ( isset( $extensions[ $extension ] ) ) {
				$path     = $extensions[ $extension ];
				$filename = W3TC_EXTENSION_DIR . '/' . str_replace( '..', '', trim( $path, '/' ) );

				if ( file_exists( $filename ) ) {
					include_once $filename;
				}
			}
		}

		if ( is_admin() ) {
			foreach ( $extensions as $extension => $path ) {
				$filename = W3TC_EXTENSION_DIR . '/' .
					str_replace( '..', '', trim( $path, '/' ) );

				if ( file_exists( $filename ) ) {
					include_once $filename;
				}
			}
		}

		w3tc_do_action( 'wp_loaded' );
		do_action( 'w3tc_extension_load' );
		if ( is_admin() ) {
			do_action( 'w3tc_extension_load_admin' );
		}

		// Hide Image Service converted images.
		$settings   = $c->get_array( 'imageservice' );
		$visibility = isset( $settings['visibility'] ) ? $settings['visibility'] : 'never';

		if ( 'never' === $visibility || ( 'extension' === $visibility && ! isset( $extensions['imageservice'] ) ) ) {
			add_action(
				'pre_get_posts',
				array( $this, 'w3tc_modify_query_obj' )
			);

			add_filter(
				'ajax_query_attachments_args',
				array( $this, 'w3tc_filter_ajax_args' )
			);
		}
	}

	/**
	 * Modify query object to hide Image Service converted images.
	 *
	 * @param object $query WP_Query object.
	 *
	 * @return void
	 */
	public function w3tc_modify_query_obj( $query ) {
		if ( ! is_admin() || ! $query->is_main_query() ) {
			return;
		}

		$screen = get_current_screen();

		if ( ! $screen || 'upload' !== $screen->id || 'attachment' !== $screen->post_type ) {
			return;
		}

		// Get the existing meta query array, add ours, and then save it.
		$meta_query   = (array) $query->get( 'meta_query' );
		$meta_query[] = array(
			'key'     => 'w3tc_imageservice_file',
			'compare' => 'NOT EXISTS',
		);

		$query->set( 'meta_query', $meta_query );
	}

	/**
	 * Filter AJAX query arguments for attachements to hide Image Service converted images.
	 *
	 * @param string $args arguments.
	 *
	 * @return void
	 */
	public function w3tc_filter_ajax_args( $args ) {
		if ( ! is_admin() ) {
			return;
		}

		$args['meta_query'] = array( // phpcs:ignore WordPress.DB.SlowDBQuery.slow_db_query_meta_query
			array(
				'key'     => 'w3tc_imageservice_file',
				'compare' => 'NOT EXISTS',
			),
		);

		return $args;
	}
}

global $w3tc_root;
if ( is_null( $w3tc_root ) ) {
	$w3tc_root = new \W3TC\Root_Loader();
	$w3tc_root->run();
}

ESTRELLA Pharma – Affy Pharma Pvt Ltd

TREPODOX

POWDER FOR ORAL SUSPENSION
30ML (HDPE BOTTLE)

Composition

Cefpodoxime 50mg/5ml

Indications & Uses

UTIs, LRTs

TREPODOX – CV

POWDER FOR ORAL SUSPENSION
30ML (GLASS BOTTLE)

Composition

Cefpodoxime 50mg + Potassium Clavulanate 31.25mg/ 5ml

Indications & Uses

Upper & lower respiratory infections, Uncomplicated skin infections, Urinary Tract Infections

ESTY CLAV

POWDER FOR ORAL SUSPENSION
30ML (GLASS +HDPE BOTTLE)

Composition

Amoxycillin 200mg + Potassium clavulanate 28.50 mg/ 5ml

Indications & Uses

Community Acquired Pneumonia, Acute Exacerbations of Chronic Bronchitis, Upper Respiratory Tract Infections, Urinary Tract Infections

ESTRIXIME – CV

POWDER FOR ORAL SUSPENSION
30ML (GLASS BOTTLE)

Composition

Cefixime 50mg + Potassium clavulanate 31.25mg/5ml

Indications & Uses

Urinary Tract Inefctions, AECB, Otitis Media, Typhoid/p>

ESTRIXIME

POWDER FOR ORAL SUSPENSION
30ML (HDPE BOTTLE)

Composition

Cefixime 50mg/5ml

Indications & Uses

Urinary Tract Inefctions, Gastroenteritis

REOMELL

ORAL SUSPENSION
15 ml

Composition

Azithromycin 200mg/5ml

Indications & Uses

Community Acquired Pneumonia, Acute Exacerbations of Chronic Bronchitis,

TAMEST – DS

ORAL SUSPENSION
60 ml

Composition

Paracetamol 250mg/5ml

Indications & Uses

Fever, Pain

STREFEN

ORAL SUSPENSION
60 ml

Composition

Paracetamol 125mg + Mefenamic Acid 50mg/5ml

Indications & Uses

Pain, Fever

STREFOX

ORAL SUSPENSION
30 ml

Composition

Ofloxacin 50mg/5ml

Indications & Uses

Acute exacerbations of chronic Bronchitis, Diarrhoea

TAMACET-P

SYRUP
60 ml

Composition

Paracetamol 125mg + PPH 5mg + Cetirizine HCI 2mg/5ml

Indications & Uses

Fever, common cold & Flu

HEPTRELL

ORAL SUSPENSION
200ml

Composition

Cyproheptadine HCI 2mg + Tricholine citrate 0.275mg/5ml

Indications & Uses

Stimulate Apetite, Induces Weight Gain, Cure Allergies

TREP-DSR

CAPSULES ( HARD GELATIN)
10X10 (Alu-Alu)

Composition

Pantoprazole 40mg (EC) + Domperidone 30mg (SR)

Indications & Uses

GERD, Dyspepsia, Acid Peptic Disorders, Gastritis

RALE-DSR

CAPSULES ( HARD GELATIN)
11X10 (Alu-Alu)

Composition

Rabeprazole 20mg (EC) + Domperidone SR

Indications & Uses

GERD, Dyspepsia, Acid Peptic Disorders, Gastritis

STRETOP-40

INJECTION
40ml

Composition

Pantoprazole Sodium 40mg + NaCL

Indications & Uses

Acid-peptic disorders in hospitalized patients, Zollinger – Ellison Syndrome, Treatment of GERD Associated with Erasive Esophagitis, GL Bleed

DIMACID

SUSPENSION
170ml

Composition

Activated Dimethicone 25mg + Magnesium Hydroxide 200mg+ Aluminium Hydroxide Gel 200mg/10ml

Indications & Uses

Heartburn, Acid Indigestion

ELLAZYME

SYRUP
200ml

Composition

Alpha Amylase (1:2000) 50mg, Pepsin(1:3000) 10mg/5ml

Indications & Uses

Dyspepsia, Flatulence, Anorexia, Pancreatic Insufficiency

ARBOLL-Z

CAPSULES (HARD GELATIN)
10X3X10

Composition

Vitamin C 75mg + Vitamin B12 5mcg + Carbonyl Iron 100mg + Folic Acid 1.5mg + Zinc Sulphate 61.8mg

Indications & Uses

Hyphocromic Anemia in Pregnancy, Chronic and / or Acute Blood Loss, Post-gynaesurgery, Iron Deficiency Anemia

EST-D3 60K

CAPSULES (SOFT GELATIN)
10X1X4

Composition

Cholecalciferol 60000 UI

Indications & Uses

Osteoporosis, Osteoarthritis, Musculoskeletal Pain, Type- 2 Diabetes, Menstrual Irregularities, Pre-eclampsia, IUGR

STREBONA

ORAL SUSPENSION
200ml

Composition

Calcium Carbonate 625mg, Vitamin D3 125 IU/5ml

Indications & Uses

Osteomalacia, Osteoporosis, Fractures, Premenstrual Syndrome

STREFE-III

SYRUP (IRON TONIC)
300 ml

Composition

Iron (III) Hydroxide Polymaltose 50mg, Folic Acid 0.5mg/15ml

Indications & Uses

Pregnancy and lactation, Iron Deficiency Anaemia, Anaemia due to Excessive Haemorrhage, Anaemia Associated with Infections and Malignant Disease

STRECIUM

CAPSULES (SOFT GELATIN)
5X2X15

Composition

Calcitriol 0.25mcg + Calcium Carbonate 500mg + Zinc Sulphate 7.5mg

Indications & Uses

Osteoporosis, Hypoparathyroidism, Pregnancy & Lactation, Premenstrual Syndrome

ESTRE-SPAS

TABLETS
20X10

Composition

Mefenamic Acid 250mg + Dicyclomine HCI 10mg

Indications & Uses

Dysmenorrhea, Irritable Bowel Syndrome, Colic and Bladder Spasm, Abdominal Pain

TAMEST-A

TABLETS (BLISTERS)
20X10

Composition

Nimeulide 100mg + Paracetamo; 325mg

Indications & Uses

Arthritis Pain, Soft Tissue Trauma Including Sprains, Musculoskeletal Pain, Pain Following Dental Extraction

PARTRA FORTE

TABLETS

20X10

Composition

Tramadol 37.5mg + Paracetamol 325mg

Indications & Uses

Chronic Back Pain, Osteoarthritis, Postoperative Pain

UMRELY GEL

GEL
30g

Composition

Diclofenac Diethylamine 1.16% w/w + Oleum Linseed Oil 3 % w/w + Menthol 5% w/w +Methyl Salicylate 10% w/w

Indications & Uses

Sprains & Strains, Lower Back Pain, Joint Pain, Knee Pain

MOISTACT

CREAM
20g

Composition

Urea 10% +Lactic Acid 10% + Propylene Glycol 10% + Liquid Paraffin 10%

Indications & Uses

Foot Cracks, Keratolytic

BELODIP

OINTMENT
15g

Composition

Clotrimazole 1% w/w + Beclomethasone Dipropionate 0.025% w/w + Neomycin 0.5% w/w

Indications & Uses

Eczema, Psoriasis, Corticosteroid Responsive Dermatoses

MIN-DAND

LOTION
100 ml

Composition

Ketoconazole 2% w/v

Indications & Uses

Pityriasis, Dandruff

MIN-DAND-Z

LOTION
100 ml

Composition

Ketoconazole Shampoo 2% w/v + ZPTO 1% w/v

Indications & Uses

Pityriasis, Dandruff

MIN-DAND

SOAP
75g

Composition

Ketoconazole 1% w/w

Indications & Uses

Tinea Versicolor, Prophylaxis of Pityriasis Versicolor

FLUTRELLA

TABLETS
20X1X1

Composition

Fluconazole 200mg

Indications & Uses

Vaginal Candidiasis, Brochopulmonary Infections, Candiduria, Tinea Pedis, Corposis, Cruris, Versicolor

ESTRAVIT

SYRUP
200ml

Composition

L-Iysine HCI 25mg + Vitamin B1 2.5mg + Vitamin B2 2.5mg + Vitamin B6 0.75mg + D-panthenol 3mg +Niacinamide 25mg + Mecobalamin 2mcg/10ml

Indications & Uses

Sub-optimal Growth, Poor Weight Gain, Malnutrition, Prolonged Illness

LYCOSTER PLUS

SYRUP
225ml

Composition

Each 10ml Contains: Lycopene 6% 1000mcg + Vitamin A Palmitate 2500 IU + Vitamin E 10 IU + Ascorbic Acid 50mg + Selenium (as Sodium Selenate) 35mcg + Zinc (As Zinc Gluconate) 3mg + Manganese (as Manganese Gluconate) 2mg + Iodine ( As Potassium Iodine) 100mcg + Copper (As Copper Sulphate0 500mcg + Thiamine HCI 2mg + Riboflavine 3mg + Pyridoxine HCI 1.5mg

Indications & Uses

Tiredness, Stress, Feeling of Weakness, Vitality Deficiency

OSERON

CAPSULES (SOFT GELATIN)
10X1X10

Composition

Antioxidant, Multivitamin & Multiminerals

Indications & Uses

Tiredness, Stress, Feeling of Weakness, Vitality Deficiency

GERMELLA

CAPSULES (SOFT GELATIN)
10X1X10

Composition

Vitamin E (Natural) 400 IU + Wheat Germ Oil 100mg + Omega 3 Fatty Acids 30mg

Indications & Uses

Ulcerative colitis, Metabolic Syndrome, Rheumatoid Arthritis, Type-2 Diabetes, Cardiovascular Diseases

LYCOSTER GOLD

CAPSULES (SOFT GELATIN)
10X1X10

Composition

Each SG Contains Lycopene 6% 2000 IU + Vitamin A 2500 IU + Vitamin E Acetate 10 IU + Vitamin C 50 mg + Zinc sulphate Monohydrate 27.45mg + Selenium Dioxide 70mcg

Indications & Uses

Idiopathic Male Infertility, Pre-eclampsia, Prostate Cancer, Cardiovascular Diseases, Diabetes Mellitus

OSERON -G

CAPSULES (SOFT GELATIN)
10X1X11

Composition

Ginseng + Multivitamin + Multimineral

Indications & Uses

Tiredness, Stress, Feeling of Weakness, Vitality Deficiency

OSERON -G

CAPSULES (SOFT GELATIN)
10X1X11

Composition

Ginseng + Multivitamin + Multimineral

Indications & Uses

Tiredness, Stress, Feeling of Weakness, Vitality Deficiency

ESTRIXIME-200 LB

TABLETS (Alu-Alu)
20X10

Composition

Cefixime 200mg + Lactic Acid Bacilus 2.5 billion spores

Indications & Uses

Otitis Media, Pharyngitis & Tonsillitis, Uncomplicated Urinary Tract Infections, Acute Exacerbations of Chronic Bronchitis, Enteric Fever

ESTRIXIME-CV-325

TABLETS (Alu-Alu)
10X1X6

Composition

Cefixime 200mg + Potassium Clavulanate 125mg

Indications & Uses

Respiratory Tract Infections, Urinary Tract Infections, Skin & Skin Structure Infections

ESTY CLAV-625 LB

TABLETS (Alu-Alu)
10X1X6

Composition

Amoxycillin 500mg + Potassium Clavulanate 125mg

Indications & Uses

Respiratory Tract Infections, Community Acquired Pneumonia, Gynaecological Infections, Acute Exacerbations of Chronic Bronchitis, Skin and Soft Tissue Infections

FLOXEST

TABLETS (Blister)
20X10

Composition

Ofloxacin 200mg + Ornidazole 500mg

Indications & Uses

Surgical ions, Diarrheas of Mixed Etiology, Gynaecological Infections, Orofacial and Dental Infections

VOFLOX-500

TABLETS
10X10

Composition

Levofloxacin 500mg

Indications & Uses

Acute Bacterial Sinusitis, Acute Bacterial Exacerbations of Chronic Bronchitis, Skin & Skin Structure Infections, Chronic Bacterial Prostatitis, Urinary Tract Infections

FLOXEST – O

TABLETS (Alu-Alu)
20X10

Composition

Cefixime 200mg + Ofloxacin 200mg

Indications & Uses

Community Acquired Pneumonia, Multiple Drug Resistant-TB, Typhoid

FLOXEST

TABLETS (Alu-Alu)
20X10

Composition

Ofloxacin 200mg

Indications & Uses

Community Acquired Pneumonia, Multiple Drug Resistant-TB, Typhoid

ESTY CLAV- 1.2

INJECTIONS
1.2g

Composition

Amoxycillin 1000mg + Potassium Clavulanate 200mg + WFI

Indications & Uses

Community Acquired Pneumonia, Gynaecological Infections, Upper Respiratory Tract Infections, Skin and Soft Tissue Infections, Urinary Tract Infections, Acute Exacerbations of Chronic Bronchitis

TRELLON-SB 1.5

INJECTIONS
1.5g

Composition

Ceftriaxone 1000mg + Sulbactam 500mg + WFI

Indications & Uses

Gynaecological Infections, Lower Respiratory Tract Infections, Intra-abdominal Infections with Aerobic Organisms, Surgical Prophylaxis

TRELLON-TZ 1.125

INJECTIONS
1.125gm

Composition

Ceftriaxone 1000mg + Tazobactam 500 mg + WFI

Indications & Uses

Bone & Joint Infections, Intra-abdominal Infections, Bacterial Meningitis, Pre-operative Surgical Prophylaxis

RELLAM

INJECTIONS
1gm

Composition

Meropenem 1gm + WFI

Indications & Uses

Complicated Intra-abdominal Infection (cIAI), Complicated Skin & Skin Structure Infections (cSSSI), Bacterial Meningitis, Noscocomial Pneumonia

TRELIN-Z 4.5

INJECTIONS
4.5gm

Composition

Piperacillin 4000mg + Tazobactam 500mg + WFI

Indications & Uses

Intra-abdominal Infections, Complicated Urinary Tract Infections, Febrile Neutropenia, Lower Respiratory Tract Infections

TRELIN-Z 4.5

INJECTIONS
4.5gm

Composition

Piperacillin 4000mg + Tazobactam 500mg + WFI

Indications & Uses

Intra-abdominal Infections, Complicated Urinary Tract Infections, Febrile Neutropenia, Lower Respiratory Tract Infections

BUTRELLA

SYRUP

100ml

Composition

Ambroxol HCI 15mg + Guaiphensin 50mg + Terbutaline Sulphate 1.5mg + Mentholated Base/5ml

Indications & Uses

Bronchitis, Productive Cough, Emphysema, Bronchial Asthma

BUTRELLA-BR

SYRUP

100ml

Composition

Terbutaline Sulphate 1.25mg + Bromhexine HCI 4mg + Guaiphenesin 50mg + Methalated Base/5ml

Indications & Uses

Acute Cough, Abnormal Mucus Secretion, Productive Cough

DEXTRIN

SYRUP
100ml

Composition

Dextromethorphan Hydrobromide 10mg + Phenylpherine 5 mg + Cetrizine 5mg + Mentholated Base/5ml

Indications & Uses

Commom Cold and Flu, Nasal Congestion, Sore Throat

VOTRELL-M

TABLETS (Alu-Alu)
20X10

Composition

Levocetirizine 5mg + Montelukast 10mg

Indications & Uses

Allergic Rhinitis, Nasal Congestion, Asthma

VOTRELL

TABLETS (Alu-Alu)
20X11

Composition

Levocetirizine 5mg

Indications & Uses

Chronic Idiopathic Urticaria (CIU), Seasonal Allergic Rhinitis (SAR), Perennial Allergic Rhinitis (PAR)

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